Bioinformatics is an emerging discipline and has applications in frontline areas of biotechnology like drug design, gene therapy, diagnostics, crop improvement, biochemical process etc. This multi-volume Encyclopaedia covers areas, such as, computational genomics, molecular modelling, statistical methods, computational techniques etc. State of the art computer systems and software tools have been used to explain different facets of Bioinformatics.
Special care has been taken to include areas starting from the very concept of bioinformatics to structural biology, computer programming, database management and communication, quantitative techniques, computational methods for sequence analysis, molecular imaging and design, genetic engineering, drug discovery, bio-spectroscopy, biophysical methods, cell and molecular biology, human physiology and Immunology. Bioinformatics has become a frontiline applied science and is of vital importance to study new biology which is widely recognized as the new scientific endeavour of the twentyfirst century. The growth in full genomic sequencing, structural genomics, proteomics, micro-array etc. will be very slow without application of bioinformatics.

Specifications:

The principal aim of the bioinformatics programme is to ensure that India emerges as a key international player in the field of bioinformatics; enabling a greater access to wealth of information created during the post-genomic era and catalyse the country's attainment of lead position in medical, agricultural, animal and environmental biotechnology. Special care has been taken for providing upto date information in this 8 Volume Encyclopaedia of Bioinformatics by first discussing Bio-Programming Languages with inputs of Computer Science, Object Oriented Programming with C and Advanced Object Oriented Programming; and then volumwise detailed description of Genetics and Genetic Engineering; Statistical Methods and Database Management System; Molecular Biology and Biochemistry; Biotechnology and Industrial Microbiology; Structural Bioinformatics including Proteins and Genome Analysis; Bio-Computing Languages with Case Studies PerlJava and BioJava; and Bioinformatics Software with a view to preparing a competent cadre of young professionals in the area of Bioinformatics.

VOLUME 1
History of Computers • Computer Architecture • Computer Software Concepts • Application Softwares for Computers
• Database Management System • Data Communications • Internet Basics • Introductory Concepts • C Fundamentals
• Operators and Expressions • Data Input and Output • Control Statements • Preparing and Running a Complete C Program • Data Abstraction • Hiding the Implementation • Initialization and Cleanup • Function Overloading and Default Arguments • Constants • Inline Functions • Name Control

VOLUME 2
Genetics and the Organism • Patterns of Inheritance • Chromosomal Basis of Heredity • Gene Interaction • Gene Manipulation: An All-embracing Technique • Basic Techniques • Cutting and Joining DNA Molecules • Basic Biology of Plasmid and Phage Vectors • Cosmids, Phasmids and other Advanced Vectors • Cloning Strategies • Sequencing and Mutagenesis • Genetics Glossary

VOLUME 3
Elementary Concepts in Statistics • Basic Statistics • Nonparametric Statistics • ANOVA/MANOVA • Process Analysis
• Survival/Failure Time Analysis • Quality Control Charts • Representative Visualization Techniques • Experimental Design (Industrial DOE) • Database-management System • Data Models • Relational Model • Relational Databases-SQL
• Database System Architectures

VOLUME 4
Systems and Methods of Molecular Biology • Macromolecules • Nucleic Acids • The Physical Structure of Protein Molecules • Macromolecular Interactions and the Structure of Complex Aggregates • The Genetic Material • DNA Replication • Repair • Transcription • Translation • Mutagenesis, Mutations, and Mutants • Biochemistry and Medicine
• Water and pH • Amino Acids and Peptides • Proteins: Determination of Primary Structure • Proteins: Higher Orders of Structure • Proteins: Myoglobin and Hemoglobin • Enzymes: Mechanism of Action • Enzymes: Kinetics • Enzymes: Regulation of Activities • Bioenergetics: The Role of ATP • Biologic Oxidation • The Respiratory Chain and Oxidative Phosphorylation • Carbohydrates of Physiologic Significance • Lipids of Physiologic Significance • Overview of Metabolism

VOLUME 5
Introduction • Animal Biotechnology • Plant Biotechnology • Social Aspects of Biotechnology • Microbial Cell Structure and Function • Microbial Growth and Nutrition • Microbial Metabolism • Industrial Microorganisms • Fermentation media
• Fermentation Systems • Downstream Processing • Product development, regulation and safety

VOLUME 6
Historical Introduction and Overview • Collecting and Storing Sequences in the Laboratory • Alignment of Pairs of Sequences • Multiple Sequence Alignment • Protein Classification and Structure Prediction • Genome Analysis

VOLUME 7
Perl, Control Flow, Motif • Basic Operators, Lists and Arrays, File Handling, Pattern Matching • Subroutines, Hashes and Application in Bioinformatics • Java for Bioinformatics • Java Programming • Object Oriented Programming • Exception Handling • Event Handling • Interfaces and Packages • Multithreading in Java • Applets and Graphics • Java Database and Connectivity • Network Programming with Java • Glossay

VOLUME 8
ClustalV Multiple Sequence Alignments • ClustalW Version 1.7 • RasMol • Oligo • Mol Script • TreeView • Alscript • Phylip • Bioinformatics Glossary • Genomic Glossary • Bioinformatics Thesaurus

Voume 9
Genetic Algorithm • Greedy Algorithms • Dynamic Programming Algorithms • Divide-and-Conquer Algorithms • Graph Algorithms • Whole-Genome Re-sequencing • Analysis of Gene Expression Data • An Eulerian Path Approach to DNA Fragment Assembly • SpecAlign-Processing and Alignment of Mass Spectra Datasets • Hidden Markov Model • Gene Finding: Putting the Parts Together • Randomized Algorithms

Voume 10
StrBioLib • Systems Biology Toolbox for MATLAB • Computational Prediction of Host-Pathogen Protein-Protein Interactions • Gapped BLAST and PSI-BLAST • PLATCOM • Computational Cluster Validation in Post-Genomic Data Analysis • A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale • CREDO • Computational Methods for the Design of Effective Therapies Against Drug Resistant HIV Strains • ChemDB • GRAST • COACH • BLAT • Comparison of Computational Methods for the Identification of Cell Cycle-Regulated genes • A Multi-Step Approach to Time Series Analysis and Gene Expression Clustering • CAFE • SBMLToolbox • Knowledge-Based Computational Search for Genes Associated with the Metabolic Syndrome